prostate-report.org

Researchers identify promising prostate cancer drug target

Scientists at Dana-Farber Cancer Institute report they have blocked the development of prostate tumors in cancer-prone mice by knocking out a molecular unit they described as a “powerhouse” that drives runaway cell growth.

The researchers said the growth-stimulating molecule called p110beta – part of a cellular signaling network disrupted in several common cancers – is a promising target for novel cancer therapies designed to shut it down.

In light of the new findings, there is likely to be great interest in finding drugs or other tools to block the p110beta protein in cancers.
Researchers hope that the task to be somewhat easier as they know what the inhibitor should look like because of their work on p110alpha inhibitors.